首页> 外国专利> DIAGNOSIS AND/OR RISK STRATIFICATION OF INFECTIONS AND CHRONIC DISEASES OF RESPIRATORY TRACT AND LUNGS BY MEANS OF PROVASOPRESSIN, PARTICULARLY COPEPTIN OR NEUROPHYSIN II

DIAGNOSIS AND/OR RISK STRATIFICATION OF INFECTIONS AND CHRONIC DISEASES OF RESPIRATORY TRACT AND LUNGS BY MEANS OF PROVASOPRESSIN, PARTICULARLY COPEPTIN OR NEUROPHYSIN II

机译:前列腺素,尤其是COPEPTIN或神经PHYSIN的诊断和/或危险性分级的呼吸道疾病和慢性病

摘要

PROBLEM TO BE SOLVED: To provide a method for diagnosing and/or stratifying the risk of infections or chronic diseases of the respiratory tract and lungs (particularly lower respiratory tract infections and chronic obstructive pulmonary diseases).SOLUTION: Provasopressin (proAVP), or fragments or partial peptides thereof, especially copeptin or neurophysin II, is/are determined. The invention further relates to suitable biomarker combinations for in-vitro diagnosis. Provasopressins (proAVPs), or fragments and partial peptides thereof, preferably copeptin or neurophysin II, demonstrate great sensitivity and specificity for the diagnosis of infections or chronic diseases of the respiratory tracts and lungs.
机译:要解决的问题:提供一种诊断和/或分层呼吸道和肺部感染或慢性疾病(特别是下呼吸道感染和慢性阻塞性肺疾病)的风险的方法。解决方案:前加压素(proAVP)或片段确定其部分肽或其肽,特别是肽素或神经纤维蛋白Ⅱ。本发明进一步涉及用于体外诊断的合适的生物标志物组合。原加压素(proAVP)或其片段和部分肽,优选肽素或神经元II,对诊断呼吸道和肺部的感染或慢性疾病显示出极大的敏感性和特异性。

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