Analysis and reductive amination of carbohydrates using 2-picoline borane as a reducing agent

摘要

The present invention, NaBH that is required by the use of (2-PB) for the reductive amination of the carbohydrate 2-picoline borane, to obtain a conversion in which the concentration of 2-PB is comparable carbohydrate (OAc I provides for the use less than the concentration of ₃ CN NaBH or) _3. The invention also provides a method of labeling a carbohydrate, which comprises the to produce carbohydrates labeled in contact with the labeled agent in the presence of 2-picoline borane (2-PB) carbohydrate . There is also provided a method of detecting a carbohydrate in a sample.