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Cyclodextrin deoxypodophyllotoxin inclusion complex, its preparation, and use in cancer treatment
Cyclodextrin deoxypodophyllotoxin inclusion complex, its preparation, and use in cancer treatment
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机译:环糊精脱氧鬼臼毒素包合物,其制备方法及在癌症治疗中的应用
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摘要
Inclusion complex of deoxypodophyllotoxin of cyclodextrin, the preparation method and the use for the treatment of cancer thereof are disclosed. The inclusion complex consists of deoxypodophyllotoxin and beta-cyclodextrin derivative, wherein the molar ration of deoxypodophyllotoxin to beta-cyclodextrin derivative is 1:1-1:10. The beta-cyclodextrin derivative is sulfobutyl ether-beta-cyclodextrin or hydroxypropyl-beta-cyclodextrin.
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