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Process for the synthesis of diarylthiohydantoin compounds and diarylhydantoin compounds
Process for the synthesis of diarylthiohydantoin compounds and diarylhydantoin compounds
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机译:二芳基硫代乙内酰脲化合物和二芳基乙内酰脲化合物的合成方法
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摘要
Processes are provided for the synthesis of diarylthiohydantoin and diarylhydantoin compounds, such as compounds of the formula: wherein X, Y 1 , Y 2 , R 1 , and R 2 are as defined herein. Medicinal products containing the same find particular use in treating prostate cancer, including castration-resistant prostate cancer and/or hormone-sensitive prostate cancer.
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