Deep brain stimulus medical therapy of mannered null high frequency in order filtering to do

摘要

Relates to a method for filtering the signal of neuronal activity Deep Brain Stimulation of high frequency (DBS) in removing the stimulus artifact in the signal is observed, the method invention, the phase space, the method comprising: approximating the signal track that has been observed, the observed signal is regarded as the sum of the stimulation artefacts induced by the stimulation signal, the stimulus signal, ordinary differential, including a self-oscillating system with stable limit cycle A process for slicing the segment is assumed to be the solution to the equation, and process, the derivatives and the observed signals, corresponding to the stimulation period, the steps, the training set, each segment, the N a step of collecting the stimulation period is selected, a step of estimating the limit cycle of oscillating system, a step of synchronizing the limit cycle is estimated the each artefact of the observed signal by the synchronization, a step of reducing the limit cycle is estimated the from each artefact in phase space, in order to obtain a total signal, which is filtered, a step of collecting all segments, and finally, to express the results in the time domain I and a step. [Selection] Figure Figure 1