首页> 外国专利> Evaluation method of prophylactic agent and / or mental illness treatment agent inspection method of mental illness, as well as test kits, mental illness for

Evaluation method of prophylactic agent and / or mental illness treatment agent inspection method of mental illness, as well as test kits, mental illness for

机译:精神疾病的预防剂和/或精神疾病治疗剂的评估方法以及检测试剂盒,精神疾病

摘要

By objective criteria based on biological indicators of methods that target a single gene, a method of evaluating the prophylactic agent and / or mental illness treatment agent inspection method of mental illness, as well as test kits, mental illness for provide. Detecting step of detecting the methylation status of the CpG island of exon I upstream of the BDNF genes of samples taken from a subject, as well as the methylation status of the sample inspection method of mental disorders of the present invention, individuals with mental illness and a test step of comparing the methylation status of the CpG island of exon I upstream of the BDNF gene in samples collected from individual non-psychiatric disorders, determines whether mental illness subject. Preferably, mental illness, schizophrenia, depression and / or.
机译:通过基于针对单个基因的方法的生物学指标的客观标准,评估精神疾病的预防剂和/或精神疾病治疗剂的检查方法以及精神疾病检测试剂盒的方法来提供。检测从受试者获取的样品的BDNF基因上游的外显子I的CpG岛的甲基化状态的检测步骤,以及本发明的精神障碍,精神病患者和精神病患者的样品检查方法的甲基化状态。比较从单个非精神病性疾病收集的样本中的BDNF基因上游外显子I的CpG岛的甲基化状态的测试步骤,确定精神疾病是否为受试者。优选地,精神疾病,精神分裂症,抑郁症和/或。

著录项

  • 公开/公告号JPWO2012017867A1

    专利类型

  • 公开/公告日2013-10-03

    原文格式PDF

  • 申请/专利权人 国立大学法人広島大学;

    申请/专利号JP20120527674

  • 发明设计人 森信 繁;淵上 学;

    申请日2011-07-26

  • 分类号C12Q1/68;C12N15/09;

  • 国家 JP

  • 入库时间 2022-08-21 16:54:17

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