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Bioartificial organ manufacturing method

机译:生物人工器官的制造方法

摘要

Disclosed is an object of the present invention is an object thereof is to provide a method for inducing differentiation into tissue cells from stem cells, to provide a bioartificial organs, including tissue cells were obtained. Furthermore, it is an object of the present invention to provide a medical material containing a bio-artificial organ made. Be to cultured by the hanging drop method using stem cells with [MEANS FOR SOLVING PROBLEMS] proliferative capacity, self-renewal ability, the ability to differentiate, cell mass of the embryoid body is constructed in three dimensions, HGF, GDNF the cell mass, By culturing in the presence of EGF and, BMP7 b-FGF, and may differentiate into tissue cells. Also, it is possible to be used to generate bioartificial organs using cells differentiated into tissue cells, to provide a medical material further. [Selection] Figure 12
机译:发明内容本发明的目的是提供一种从干细胞诱导分化为组织细胞的方法,以提供包括组织细胞在内的生物人工器官。此外,本发明的目的是提供包含制成的生物人工器官的医疗材料。要使用具有[解决问题的手段]增殖能力,自我更新能力,分化能力的干细胞通过悬滴法进行培养,应在三个维度上构建胚状体的细胞质量,HGF,GDNF是细胞质量,通过在EGF和BMP7 b-FGF的存在下培养,可分化为组织细胞。同样,可以使用分化为组织细胞的细胞来产生生物人工器官,以进一步提供医学材料。 [选择]图12

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