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A method for recovering anticancer drug sensitivity of cancer cells that have acquired anticancer drug resistance

机译:恢复已获得抗癌药耐药性的癌细胞的抗癌药敏感性的方法

摘要

The present invention relates to a method for restoring cisplatin sensitivity to cancer cells that have acquired resistance to cisplatin, and an RNAi vector that can express an FGF13 gene expression inhibitor, for example, an RNAi substance that targets the FGF13 gene, in the cell. The present invention provides a method for recovering the cisplatin sensitivity of cancer cells that have acquired cisplatin resistance by using a pharmaceutical composition containing as an active ingredient, and an anticancer therapeutic method that suppresses the ability to acquire cisplatin resistance when used in combination with cisplatin. [Selection figure] None
机译:本发明涉及恢复顺铂对已获得对顺铂耐药性的癌细胞的敏感性的方法,以及可在细胞中表达FGF13基因表达抑制剂的RNAi载体,例如靶向FGF13基因的RNAi物质。本发明提供了一种通过使用包含作为活性成分的药物组合物来恢复已获得顺铂耐药性的癌细胞的顺铂敏感性的方法,以及与顺铂组合使用时抑制获得顺铂耐药性的能力的抗癌治疗方法。 [选择图]无

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