Biomarker diagnosis of chronic schizophrenia in the presence of cognitive impairment is confirmed when Phosphocreatine (PCr) levels are increased, compared to normal levels, in both the left and right prefrontal cortices of the brain, with increased PCr specifically also in the left basal ganglia and also reduced NA/Crt in the left superior temporal region of the brain. Biomarker differential diagnosis is also taught for chronic alcoholism (with or without cognitive impairment) and for chronic schizophrenia even when cognitive impairment is absent.
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机译：与正常水平相比，大脑左前额叶皮层和右前额叶皮层中的磷酸肌酸（PCr）水平升高，证实了存在认知障碍的慢性精神分裂症的生物标志物诊断，尤其是在左基底神经节和右叶中也降低了大脑左颞上区的NA / Cr t 。即使没有认知障碍，也可以教授生物标志物鉴别诊断方法，用于慢性酒精中毒（有或没有认知障碍）和慢性精神分裂症。
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