首页> 外国专利> THE NOVEL ABETA22(pE)-42 PEPTIDE THAT BINDS TO AMYLOID-BETA ANTIBODY SPECIFICALLY IN BLOOD AND PHARMACEUTICAL COMPOSITION FOR THE DIAGNOSIS OF DEMENTIA DISEASE CONTAINING THE SAME AS AN ACTIVE INGREDIENT

THE NOVEL ABETA22(pE)-42 PEPTIDE THAT BINDS TO AMYLOID-BETA ANTIBODY SPECIFICALLY IN BLOOD AND PHARMACEUTICAL COMPOSITION FOR THE DIAGNOSIS OF DEMENTIA DISEASE CONTAINING THE SAME AS AN ACTIVE INGREDIENT

机译:新型ABETA22(pE)-42肽,特别结合在血液和药物成分中,与淀粉样蛋白抗体结合,用于诊断老年痴呆症,并将其作为一种活性成分

摘要

The present inventors screened peptides having a specific sequence specifically binding to amyloid-beta antibody and accordingly confirmed that Aβ22(pE)-42 peptide showed higher reactivity to amyloid-beta antibody in serum of Alzheimer's disease patients. Therefore, the said Aβ22(pE)-42 peptide can be used as an active ingredient for the kit for diagnosing dementia and thus it can be said that the peptide can be effectively used for the diagnosis of dementia whose early diagnosis is hardly possible.
机译:本发明人筛选了具有与淀粉样β抗体特异性结合的特定序列的肽,因此证实了Aβ22(pE)-42肽在阿尔茨海默氏病患者的血清中显示出对淀粉样β抗体的更高反应性。因此,所述Aβ22(pE)-42肽可以用作痴呆诊断试剂盒的活性成分,因此可以说该肽可以有效地用于痴呆的诊断,而早期诊断几乎不可能。

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