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TREATMENT OF DISEASES BY EPIGENETIC REGULATION
TREATMENT OF DISEASES BY EPIGENETIC REGULATION
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机译:通过表观调节治疗疾病
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摘要
The present disclosure provides non-naturally occurring polyphenol compounds that inhibit the bromodomain and extra terminal domain (BET) proteins. The disclosed compositions and methods can be used for treatment and prevention of cancer, including NUT midline carcinoma, Burkitt's Lymphoma, Acute Myelogenous Leukemia, and Multiple Myeloma; autoimmune or inflammatory diseases or conditions, and sepsis.
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