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MODULATION OF CYTOKINE-INDUCED CHRONIC INFLAMMATORY RESPONSES
MODULATION OF CYTOKINE-INDUCED CHRONIC INFLAMMATORY RESPONSES
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机译:细胞因子诱导的慢性炎症反应的调节
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摘要
A composition for treatment of a chronic inflammation condition or an autoimmune disorder wherein the composition comprises a therapeutically effective amount of a polypeptide molecule comprising an amino acid sequence that shares at least 80% sequence identity with an amino acid sequence selected from SEQ ID NO: 21, SEQ ID NO: 22, SEQ ID NO 23, and SEQ ID NO: 23. A composition for treatment of a chronic inflammation condition or an autoimmune disorder wherein the composition comprises a therapeutically effective amount of an analog of a LL-37 peptide molecule. A composition for treatment of a chronic inflammation condition or an autoimmune disorder wherein the composition comprises a therapeutically effective amount of an exogenous agonist for increasing cellular production and/or cellular activation and/or cellular expression of a LL-37 peptide. Use of one or more of the compositions for treatment of a chronic inflammation condition or an autoimmune disorder.
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机译:用于治疗慢性炎症或自身免疫疾病的组合物,其中所述组合物包含治疗有效量的多肽分子,所述多肽分子包含与选自SEQ ID NO:21的氨基酸序列具有至少80%序列同一性的氨基酸序列,SEQ ID NO:22,SEQ ID NO 23和SEQ ID NO:23。用于治疗慢性炎症或自身免疫疾病的组合物,其中所述组合物包含治疗有效量的LL-37肽分子的类似物。 。用于治疗慢性炎症或自身免疫疾病的组合物,其中所述组合物包含治疗有效量的外源激动剂,用于增加LL-37肽的细胞产生和/或细胞活化和/或细胞表达。一种或多种组合物在治疗慢性炎症或自身免疫疾病中的用途。
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