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Method for aligning cells and applying homogenous strain throughout deformable engineered tissue constructs
Method for aligning cells and applying homogenous strain throughout deformable engineered tissue constructs
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机译:在整个可变形的工程组织结构中排列细胞并施加同质应变的方法
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摘要
A process creates a homogenous sheet of engineered tissue comprised of encapsulated cells and a deformable engineered tissue construct. In the embodiment consisting of a collagen construct with encapsulated cells capable of contracting the matrix, the collagen fibers and encapsulated cells are aligned during the process. An apparatus can deliver controlled homogenous strain and stress to a thin sheet of engineered tissue. This process allows application of dynamic, uniform tensile loading to deformable engineered tissue constructs and creation of an engineered cell-delivery construct with alignment of both fibers and encapsulated cells.
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