The present invention provides a method and system for continuous separation and purification of ganoderic acids and polysaccharides, which, via the help of supercritical fluid technology, could feed continuously Ganoderma extract and supercritical solvents at a predefined rate into a separator under operating pressure 10-30 MPa and temperature 40-60° C.; then ganoderic acids, polyphenols and polysaccharides can be separated from Ganoderma extract in the separator; with introduction of membrane purification technology, ganoderic acids, polyphenols and polysaccharides are fed continuously to different purifiers to obtain high-purity ganoderic acids, polyphenols and polysaccharides.
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