Total Internal Reflection Photoacoustic Spectroscopy

摘要

A system and method of conducting total internal reflection photoacoustic spectroscopy (TIRPAS) comprising using a pulsed laser source to emit a thermally or stress confined laser beam at a prism comprising a surface to be in contact with a sample such that the laser beam travels through the prism to a location at an interface between the prism and the sample to form an evanescent field extending into the sample to generate a detectable photoacoustic response to the evanescent field by an analyte in the sample.