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METHOD OF SYNERGISTICALLY ENHANCING THE THERAPEUTIC EFFICACY AND SAFETY OF MEDICATION THROUGH A COMBINATION THERAPY
METHOD OF SYNERGISTICALLY ENHANCING THE THERAPEUTIC EFFICACY AND SAFETY OF MEDICATION THROUGH A COMBINATION THERAPY
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机译:通过组合疗法协同增强治疗功效和药物安全性的方法
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摘要
The present invention provides combinations, for treatment of subjects suffering from or at high risk of developing diseases and disorders involving expression of peroxisome proliferator-activated receptors (PPAR). The combinations include abscisic acid and one other bioactive agent, which together provide synergistic effects toward treatment or blocking of development of the disease or disorder. In exemplary embodiments, a combination of abscisic acid and a thiazolidinedione (TZD) is provided for increased insulin sensitivity and improved (i.e., reduced) obesity-induced inflammation.
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