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Methods of specifying mesodermal, endodermal and mesoendodermal cell fates
Methods of specifying mesodermal, endodermal and mesoendodermal cell fates
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机译:指定中胚层,内胚层和中胚层细胞命运的方法
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摘要
We disclose a method for producing a mesodermal or a endodermal cell from a pluripotent stem cell, the method comprising activating a Wnt signalling pathway in the pluripotent stem cell. In some embodiments, the pluripotent stem cell is in a substantially 2 dimensional configuration, such as a monolayer, for at least a portion of the time when the Wnt signalling pathway is activated.
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