An MRI system and method for imaging perfusion in an arterial spin labeled (ASL) process in which multiplexed echo-planar imaging (M-EPI) is used rather than conventional EPI, to thereby speed up imaging and generate sets of images that show different phases of perfusion and provide additional benefits. A single multiband RF excitation pulse can be used to excite multiple slices for imaging, or a time sequence of multiband pulses can be used to further increase the number of slices.
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