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PHARMACEUTICAL COMPOSITIONS BASED ON DICLOFENAC
PHARMACEUTICAL COMPOSITIONS BASED ON DICLOFENAC
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机译:基于双氯芬酸的药物成分
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摘要
New pharmaceutical compositions for oral use containing Diclofenac together with alkali metal bicarbonates in amounts of from 20 to 80 by weight with respect to Diclofenac are described. These compositions are entirely palatable and free from any unpleasant taste or other side effects; in particular, these formulations permit to obtain in human patients higher Cmax of the active principle and shorter Tmax together with a lower coefficient of variation.
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机译:描述了含有双氯芬酸和碱金属碳酸氢盐的量相对于双氯芬酸为20至80重量%的新型口服组合物。这些组合物完全可口,并且没有任何令人不快的味道或其他副作用。特别地,这些制剂允许在人类患者中获得较高的有效成分的C max Sub>和较短的T max Sub>,同时具有较低的变异系数。
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