TREATMENT OF POLYCYSTIC OVARY SYNDROME USING RENAL NEUROMODULATION AND ASSOCIATED SYSTEMS AND METHODS

摘要

Methods for treating polycystic ovary syndrome with therapeutic renal neuromodulation and associated systems and methods are disclosed herein. The polycystic ovary syndrome can be associated, for example, with a condition including at least one of oligo/amenorrhea, infertility, hirsutism, obesity, metabolic syndrome, insulin resistance, and increased cardiovascular risk profile. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate a renal artery of a kidney of a patient. Central sympathetic drive in the patient can thereby be reduced in a manner that treats the patient for the polycystic ovary syndrome. Renal sympathetic nerve activity can be modulated along the afferent and/or efferent pathway. The modulation can be achieved, for example, using an intravascularly positioned catheter carrying a therapeutic assembly, e.g., a therapeutic assembly configured to cryotherapeutically cool the renal nerve or to deliver an energy field to the renal nerve.