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Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment of type 2 diabetes

机译:β-氨基杂环二肽基肽酶抑制剂用于治疗2型糖尿病

摘要

The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
机译:本发明涉及作为二肽基肽酶-IV酶的抑制剂(“ DP-IV抑制剂”)并且可用于治疗或预防涉及二肽基肽酶-IV酶的疾病例如糖尿病的化合物。特别是2型糖尿病。本发明还涉及包含这些化合物的药物组合物,以及这些化合物和组合物在预防或治疗涉及二肽基肽酶-IV酶的疾病中的用途。

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