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Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells

机译:通过鼻内施用脐带源细胞治疗中风和其他急性神经退行性疾病

摘要

This invention relates to methods of treating stroke by intranasal administration of umbilical cord tissue-derived cells, which are isolated from mammalian umbilical cord tissue substantially free of blood or expanded in culture from a cell isolated from mammalian umbilical cord tissue substantially free of blood, are capable of self-renewal and expansion in culture, and do not produce CD117 and/or telomerase. The methods of the invention regenerate, repair and improve neural tissue and improve behavior and neurological function in stroke patients.
机译:本发明涉及通过鼻内施用脐带组织来源的细胞来治疗中风的方法,所述细胞是从基本上无血的哺乳动物脐带组织中分离的,或者是从从基本上无血的哺乳动物脐带组织中分离的细胞中培养而扩增的。具有自我更新和扩展能力,并且不产生CD117和/或端粒酶。本发明的方法在中风患者中再生,修复和改善神经组织并改善行为和神经功能。

著录项

  • 公开/公告号US8518390B2

    专利类型

  • 公开/公告日2013-08-27

    原文格式PDF

  • 申请/专利权人 BRIAN C. KRAMER;ANTHONY J. KIHM;

    申请/专利号US201113184378

  • 发明设计人 BRIAN C. KRAMER;ANTHONY J. KIHM;

    申请日2011-07-15

  • 分类号C12N5;C12N5/071;

  • 国家 US

  • 入库时间 2022-08-21 16:46:24

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