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Efficient generation of neural progenitors, neurons, and dopaminergic neurons from human embryonic stem cells

机译:从人类胚胎干细胞有效生成神经祖细胞,神经元和多巴胺能神经元

摘要

The present invention relates to a method for inducing the differentiation of neural progenitors, neurons, and dopaminergic neurons from human embryonic stem cells with high efficiency, in which neural selection can be performed by the selected media and physical methods. The invention has advantages such as higher efficiency, the effect of lowering cost and time, and maintenance of neural progenitors for a longer period of time, as compared to the known methods for inducing the differentiation into neural progenitors, neurons, and dopaminergic neurons. Accordingly, the method can stably generate cells used for treating Parkinson's disease or other nervous system diseases.
机译:本发明涉及一种高效诱导人胚胎干细胞分化神经祖细胞,神经元和多巴胺能神经元的方法,其中可以通过选择的培养基和物理方法进行神经选择。与诱导分化为神经祖细胞,神经元和多巴胺能神经元的已知方法相比,本发明具有诸如更高的效率,降低成本和时间的效果以及在更长的时间内维持神经祖细胞的优点。因此,该方法可以稳定地产生用于治疗帕金森氏病或其他神经系统疾病的细胞。

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