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Use of perifosine in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals

机译:利福磷与抗代谢物联合用于治疗人类和哺乳动物的良性和恶性肿瘤

摘要

The invention relates to the use of alkylphosphocholines in combination with antimetabolite antitumor substances for the treatment of benign and malignant oncoses in humans and animals. It is possible in this connection for the alkylphosphocholines to be employed in a combination according to the invention with one or more antimetabolite antitumor substances. Preferred alkylphosphocholines are described by the Formula II.; embedded image ;One such preferred alkylphosphocholine is perifosine.
机译:本发明涉及烷基磷酸胆碱与抗代谢物抗肿瘤物质联合用于治疗人和动物的良性和恶性肿瘤的用途。就此而言,烷基磷酸胆碱可能与一种或多种抗代谢物抗肿瘤物质一起用于本发明。优选的烷基磷胆碱由式II描述。 “嵌入式图像” ;一种这样的优选的烷基磷酸胆碱是哌福辛。

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