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Eprosartan mesylate crystalline particles and a process for preparing pure eprosartan

机译:甲磺酸依普罗沙坦的结晶颗粒和制备纯依普罗沙坦的方法

摘要

The present invention relates to eprosartan mesylate particles having a relatively larger surface area, to the methods for the manufacture of said crystalline particles, and to pharmaceutical compositions comprising said crystalline particles. The present invention further relates to a crystalline solid of eprosartan acetate, to a process for its preparation and to a pharmaceutical composition comprising it. The present invention also provides substantially pure eprosartan free base and a process for its preparation.
机译:本发明涉及具有相对较大表面积的依普罗沙坦甲磺酸盐颗粒,制备所述晶体颗粒的方法以及包含所述晶体颗粒的药物组合物。本发明进一步涉及醋酸依普罗沙坦的结晶固体,其制备方法以及包含它的药物组合物。本发明还提供了基本上纯的依普罗沙坦游离碱及其制备方法。

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