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Liposome for liver-specific delivery and release of therapeutic nucleic acids or drugs

机译:脂质体可用于肝脏特异性递送和释放治疗性核酸或药物

摘要

Disclosed herein is a composite of a nanoscale particle size. The composite is able to specifically deliver therapeutic agents such as therapeutic nucleic acids or drugs to the liver and selectively release them into hepatic cells to manifest potent therapeutic effects of the therapeutic agents. The composite may be comprised of an apolipoprotein A-1 and a liposome-forming material. A composition containing the composite and a pharmaceutically acceptable carrier is disclosed.
机译:本文公开了纳米级粒度的复合物。该复合物能够将诸如治疗性核酸或药物的治疗剂特异性地递送至肝脏,并选择性地将其释放到肝细胞中以表现出治疗剂的有效治疗效果。该复合物可以由载脂蛋白A-1和脂质体形成材料组成。公开了一种包含复合物和药学上可接受的载体的组合物。

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