Sequences of amino acids of protein imunogu00canicas detoxificadas, plasmu00cddeo recombinant veterinary pharmaceutical formulations and / or containing the derivative of toxin heat lu00c1bil (ltk4r) and its uses,

摘要

Sequu00cancias of amino acids of protein imunogu00canicas detoxificadas, plasmu00cddeo recombinant veterinary pharmaceutical formulations and / or containing the derivative of toxin heat lu00c1bil (ltk4r) and its uses. The present invention provides sequences of amino acids of proteins imunogu00eanicas detoxificadas (SEQ. ID. 1 to SEQ. ID.(4) the subunit A1, attenuated and derived from termolu00e1bil toxin (LT) of escherichu00eda coli (ETEC) containing enterotoxigu00eanica changes of amino acid at position 4, particularly, the exchange of the plant for an arginine (k4r), combined LT4) or not (ltk4r) to changes in the area A2 (k213e, N2 38d) and subunit B (s4t, a46e, e1o2k)The recombinant plasmid and veterinary pharmaceutical formulations and / or, preferably, vaccines.In addition, this patent application is for the use of the sequences and / or plasmideo recombinant encoding for LT4 ltk4r as vaccine adjuvants and / or other assets of interest and / or in the preparation of vaccine formulations applied in prophylactic or therapeutic control of diseases. Non infectious and / or infectious.