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PHARMACEUTICAL COMPOSITION COMPRISING OLIGO-GULURONATE OR GALACTURONATE, METHODS OF TREATMENT USING SAME, USE THEREOF AND SPRAY APPLICATOR COMPRISING SAME
PHARMACEUTICAL COMPOSITION COMPRISING OLIGO-GULURONATE OR GALACTURONATE, METHODS OF TREATMENT USING SAME, USE THEREOF AND SPRAY APPLICATOR COMPRISING SAME
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机译:含低聚古龙酸酯或半乳糖醛酸酯的药物组合物,使用相同的治疗方法,使用其组成和相同的喷雾施药器
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摘要
The invention provides a pharmaceutical composition comprising a macromolecular drug and an oligoguluronate or oligogalacturonate, e.g. having a number average degree of polymerization in the range 5 to 18, a guluronate (or galacturonate) fraction (FG)of at least 0.80, a mannuronate fraction (FM) of no more than 0.20, and having at least 95% mole with a degree of polymerization less than 20. The composition may be used in a method of treatment which comprises administering the composition to a mucosal surface in a human or non-human vertebrate subject.
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