KINAZOLINE DERIVATIVES AS IRREVERSIBLE INHIBITORS OF PROTEIN-KINASE, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND USE THEREOF

摘要

The present invention provides compounds that are irreversible inhibitors of tyrosine kinases. Also provided is a method of treating cancer, restenosis, atherosclerosis, endometriosis, and psoriasis and a pharmaceutical composition that comprises a compound that is an irreversible inhibitor of tyrosine kinases.