首页> 外国专利> NOVEL 1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES AND THEIR USE AS LIGANDS FOR V1B AND V1A ARGININE-VASOPRESSIN RECEPTORS

NOVEL 1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES AND THEIR USE AS LIGANDS FOR V1B AND V1A ARGININE-VASOPRESSIN RECEPTORS

机译:新型1,3-二氢-2H-吲哚-2-酮衍生物及其作为V1B和V1A精氨酸-血管加压素受体的配体的用途

摘要

The invention relates to compounds of formula: as well as the possible salts thereof with mineral or organic acids, and the solvates and/or hydrates thereof, which have affinity for and selectivity towards the V1b receptors or towards both the V1b and V1a receptors of arginine-vasopressin. The invention also relates to the process for preparing them, to the intermediate compounds of formula (II) that are useful for preparing them, to pharmaceutical compositions containing them and to their use for the preparation of medicinal products.
机译:本发明涉及下式的化合物:以及与无机或有机酸的可能的盐,及其溶剂化物和/或水合物,其对精氨酸的V1b受体或V1b和V1a受体均具有亲和性和选择性-加压素。本发明还涉及制备它们的方法,可用于制备它们的式(II)中间体化合物,包含它们的药物组合物以及它们在制备医药产品中的用途。

著录项

  • 公开/公告号HU229081B1

    专利类型

  • 公开/公告日2013-07-29

    原文格式PDF

  • 申请/专利权人 SANOFI-AVENTIS;

    申请/专利号HU20020004242

  • 申请日2001-01-24

  • 分类号C07D403/04;A61K;A61K31/404;A61K31/405;A61K31/496;A61K31/5377;A61P;A61P1;A61P1/18;A61P3/06;A61P3/08;A61P5/38;A61P5/50;A61P7/04;A61P9;A61P9/10;A61P9/12;A61P11/06;A61P13/02;A61P15/04;A61P15/12;A61P17/06;A61P25;A61P25/02;A61P25/06;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P27/12;A61P29;A61P35;A61P37/06;A61P37/08;A61P43;C07D;C07D207/12;C07D209/04;C07D209/34;C07D403/14;C07D405/06;C07D405/14;

  • 国家 HU

  • 入库时间 2022-08-21 16:41:40

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