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Injectable composition for the extended release of aripiprazole and use of a mixture of aripiprazole in an injection vehicle
Injectable composition for the extended release of aripiprazole and use of a mixture of aripiprazole in an injection vehicle
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机译:用于阿立哌唑缓释的可注射组合物以及阿立哌唑混合物在注射载体中的用途
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摘要
The present invention relates, in part, to the discovery that a pharmaceutical composition comprising aripiprazole and a carrier administered in a bolus injection resulted in an extended release profile similar to that obtained by the injection of a polylactide-co-glycolide microsphere formulation containing the active agent. This surprising result provides pharmacologically beneficial extended release formulations without the complexities and expense associated with the manufacture of microspheres.
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