CELL-CULTURE IN 2-DIMENSIONAL CONSTRUCTS CONSISTING OF T-CELLS, B-CELLS, ANTIGEN-PRIMED DENDRITIC CELLS AND OPTIONALLY FOLLICULAR DENDRITIC CELLS AND METHODS FOR TESTING IMMUNE RESPONSES TO ANTIGENS

摘要

The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologies and other chemicals.