The present invention is concerned with substituted imidazo[l,5-a][l,2,4]triazolo[l,5-d][l,4]benzodiazepine derivatives of the following formula wherein the definition of substituents is described in the claims. It has been found that this class of compounds show high affinity and selectivity for GABA A a5 receptor binding sites and might be useful as cognitive enhancer or for the treatment of cognitive disorders like Alzheimer"s disease.
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机译：本发明涉及下式的取代的咪唑并[1，5-a] [1，2，4]三唑并[1，5-d] [1，4]苯并二氮杂衍生物，其中取代基的定义在索赔。已经发现这类化合物对GABA A a5受体结合位点显示出高亲和力和选择性，并且可以用作认知增强剂或用于治疗诸如阿尔茨海默氏病的认知障碍。
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