Kinazolinderivater, metode for fremstilling av slike samt mellomprodukter, farmasøytiske preparater omfattende slike, slike forbindelser for anvendelse som medikament samt anvendelse av slike for fremstilling av medikament for behandling av sykdom

摘要

The invention concerns quinazoline derivatives of Formula (I): wherein each of R1, X1, R2, R3, R5, n and m have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumors which are sensitive to inhibition of EGF and erbB receptor tyrosine kinases.