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COMPOSITIONS AND METHODS FOR TREATING HEPATITIS B VIRUS INFECTION comprising lamivudine and adefovir dipivoxil
COMPOSITIONS AND METHODS FOR TREATING HEPATITIS B VIRUS INFECTION comprising lamivudine and adefovir dipivoxil
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机译:用于治疗乙型肝炎病毒感染的组合物和方法,包括拉米夫定和阿德福韦酯
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601519 Disclosed is a pharmaceutical composition for treating hepatitis B virus infection in a human, comprising: a first active pharmaceutical ingredient consisting of more than 400 mg to about 1500 mg of lamivudine, (2R,cis)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-pyrimidin-2-one, or a therapeutically equivalent amount of a pharmaceutically acceptable salt or ester thereof; and a second active pharmaceutical ingredient consisting of about 1 mg to about 10 mg of adefovir dipivoxil, bis(pivaloyloxymethyl)(9-[(R)-2(phosphonomethoxy)ethyl] adenine, or a therapeutically equivalent amount of a pharmaceutically acceptable salt or ester thereof.
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