首页> 外国专利> Citrate salt of 9E-15-(2-pyrrolidin-1-yl-ethoxy)-7,12,25-trioxa-19,21,24-triaza-tetracycloh18.3.1.1(2,5).1(14,18)Essecos a-1(24),2,4,9,14,16,18(26),20,22-nonaene

Citrate salt of 9E-15-(2-pyrrolidin-1-yl-ethoxy)-7,12,25-trioxa-19,21,24-triaza-tetracycloh18.3.1.1(2,5).1(14,18)Essecos a-1(24),2,4,9,14,16,18(26),20,22-nonaene

机译:9E-15-(2-吡咯烷-1-基乙氧基)-7,12,25-三氧杂-19,21,24-三氮杂-四环h18.3.1.1(2,5).1(14, 18)Essecos a-1(24),2,4,9,14,16,18(26),20,22-壬烯

摘要

The present invention relates to certain salts of a 9E-15-(2-pyrrolidin-1-yl-ethoxy)-7,12,25-trioxa-19,21,24-triaza-tetracyclo[18.3.1.1(2,5).1(14,18)]hexacosa-1(24),2,4,9,14,16,18(26),20,22-nonaene (Compound I) which have been found to have improved properties. In particular the present invention relates to the citrate salt of this compound. The invention also relates to pharmaceutical compositions containing the citrate salt and methods of use of the citrate salt in the treatment of certain medical conditions.
机译:本发明涉及9E-15-(2-吡咯烷-1-基-乙氧基)-7,12,25-三氧杂-19,21,24-三氮杂-四环[18.3.1.1(2,5) ).1(14,18)] hexacosa-1(24),2,4,9,14,16,18(26),20,22-壬二烯(化合物I)已发现具有改善的性能。特别地,本发明涉及该化合物的柠檬酸盐。本发明还涉及含有柠檬酸盐的药物组合物,以及柠檬酸盐在某些医学病症的治疗中的使用方法。

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