2-АМІНО-5,5-ДИФТОР-5,6-ДИГІДРО-4H-ОКСАЗИНИ ЯК ІНГІБІТОРИ BACE1 І/АБО BACE22-АМИНО-5,5-ДИФТОР-5,6-ДИГИДРО-4H-ОКСАЗИНЫ КАК ИНГИБИТОРЫ BACE1 И/ИЛИ BACE2

摘要

The present invention relates to 2-Amino-5,5-difluoro-5,6-dihydro-4H-[1,3]oxazin-4-yl)-phenyl]-amide derivatives of formula (I) having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes. EMBED ISISServer , (I)