surfactant system to enhance absorption of the antibacterial agent on dental tissue

摘要

An oral composition exhibiting increased uptake by dental tissue of antibacterial compounds contained therein, the composition comprising in an orally acceptable vehicle an effective therapeutic amount of an antibacterial compound halogenated diphenyl ether or phenolic and a mixture of anionic and zwitterionic, incorporating the antibacterial agent in the composition in a concentration of 0.05 to 2.0% by weight and the anionic surfactant being present in the composition in a concentration of 1.5 to 3% weight and the zwitterionic surfactant being present in the composition in a concentration of 0.10 to 0.50% by weight, wherein the zwitterionic surfactant is a cocoamido propyl betaine.