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A method for obtaining data useful in identifying a patient at risk of having difficulty carrying a pregnancy to term

机译:一种用于获取数据的方法,该数据可用于识别有可能难以进行妊娠的危险的患者

摘要

stimulating factor granulocyte colony (G-CSF) for use in a method of treating a conriesgo woman implantation failure during assisted reproduction and / or spontaneous abortion, comprising dichométodo: determining, in a sample of said patient, least one of the parameters selected from the group queconsiste cell numbers Th1, Th2 cell number, activity of Th1 cells, Th2 cell activity, a product tHE aMOUNT Th1 cells, and the amount of a product of Th2 cells; identifying whether said sample satisfies one or more criteria selected from the group consisting of Th1 high decélulas number, activity elevated Th1 cells, high amount of a product of Th1 cells, decélulas number Th2 decreased Th2 cell activity decreased, decreased amount a product of Th2 cells, unamayor number ratio Th1 cells to Th2 cells number, and increased Th1 cell activity to Th2 activity decélulas; and if the sample meets one or more of these criteria, G-CSF is administered at a dose of 1 to 20 mcg (micrograms) / kg / day to said patient.
机译:刺激因子粒细胞集落(G-CSF),用于在辅助生殖和/或自然流产过程中治疗长颈鹿妇女着床失败的方法中,包括二通体:在所述患者的样本中,确定选自以下参数中的至少一个:组queconsistive细胞数目Th1,Th2细胞数目,Th1细胞活性,Th2细胞活性,ThHEaMOUNT Th1细胞的乘积和Th2细胞乘积的量;鉴定所述样品是否满足选自以下条件的一项或多项标准:Th1高十倍体数,Th1细胞活性升高,Th1细胞积高量,Th2细胞十倍体数降低,Th2细胞活性降低,Th2细胞积量降低,无数目的Th1细胞与Th2细胞数目之比,以及增加的Th1细胞活性与Th2细胞活性的关系。并且如果样品满足这些标准中的一项或多项,则以1至20 mcg(微克)/ kg /天的剂量向该患者给药G-CSF。

著录项

  • 公开/公告号ES2405506T3

    专利类型

  • 公开/公告日2013-05-31

    原文格式PDF

  • 申请/专利权人 NORA LLC;NORA THERAPEUTICS INC.;

    申请/专利号ES20100159565T

  • 发明设计人 CARTER DARRYL L.;

    申请日2004-10-25

  • 分类号A61K38/00;A61Knull/null;A61K35/28;C07K5/04;C07K14/00;G01N33/68;

  • 国家 ES

  • 入库时间 2022-08-21 16:38:38

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