COMBINATION OF FLUPIRTINE AND TOLPERISONE OR EPERISONE FOR THE TREATMENT OF PAINFUL CONDITIONS

摘要

The invention relates to pharmaceutical combinations of potassiumchannel openers and sodium channel inhibitors for the treatmentof painful conditions associated with elevated muscle tone.Provided is a pharmaceutical composition comprising flupirtine ina synergistic combination with tolperisone or its analogepenisone for the treatment of a painful condition associatedwith elevated muscle tone. The combination of the invention makesthe treatment of painful conditions associated with elevatedmuscle tone more effective and safe.