BLOCK COPOLYMERS OF POLYCAPROLACTONE AND POLY (PROPYLENE FUMARATE)

摘要

Poly(propylene fumarate) is copolymerized with poly(caprolactone) diol toproduce a block copolymer of poly(propylene fumarate) and poly(caprolactone).The biocompatible and bioresorbable block copolymer of poly(propylenefumarate) and poly(caprolactone) is useful in the fabrication of injectableand in~ situ hardening scaffolds for tissue and/or skeletal reconstruction.The block copolymer can be crosslinked by redox or photo-initiation, with orwithout an additional crosslinker. Thus, the copolymer is both self-crosslinkable (without the use of any crosslinkers) and photocrosslinkable (inthe presence of photons such as UV light).