Pharmaceutical composition comprising (E) -7- 4- (4-fluorophenyl) -6-isopropyl-2- methyl (methylsulfonyl) amino pyrimidin-5 -yl- (3R, 5S) -3, 5-dihydr0xyhept-6-en0ic acid

摘要

A chemically stable formulation of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2- [methyl(methylsulfonyl)amino]pyrim idin-5-yl]-(3R, 5S)-3,5-dihydroxyhept-6-enoic acid or a pharmaceutically-acceptable salt thereof for oral use, such as tablets, capsules, powders, granules has been developed using the substances which stabilize against formation of degradation products: lactone and oxidation product.