CORTICAL BONE SCAFFOLD FOR GUIDED OSTEON REGENERATION IN LOAD-BEARING ORTHOPAEDIC APPLICATIONS

摘要

Described is an artificial bone scaffold with an architecture resembling cortical bone, including microchannel-like structures resembling osteons. The scaffold enhances the ability of osteoblasts to secrete organized collagen and mineralize extracellular matrix within the osteon-like channels, thus promoting scaffold strength.