DIGITAL MICROFLUIDIC CHIPS FOR AUTOMATED HYDROGEN DEUTERIUM EXCHANGE (HDX) MS ANALYSIS

摘要

Described herein is a digital microfluidic droplet generator (DMDG) and a microfluidic platform for processing material introduced into the DMDG. The combination is particularly suited for hydrogen/deuterium exchange and mass spectrometer (HDX-MS) processing and analysis of membrane proteins.