METHOD FOR TRACKING OF CONTRAST ENHANCEMENT PATTERN FOR PHARMACOKINETIC AND PARAMETRIC ANALYSIS IN FAST-ENHANCING TISSUES USING HIGH-RESOLUTION MRI

摘要

A method for performing a high-resolution pharmacokinetic analysis for calculation of tissue parameters for a fast-enhancing tissue enables medical personal to accuratley determine pharmacokinetic parameters in fast-enhancing tissues (1200). The method includes obtaining mask image data of the tissue when it is in a steady state condition, obtaining a time series of image data of the tissue when the contrast agent is flowing in the tissue, and increasing a spatial resolution (1220) of the time series of image data using the mask image data to obtain a time series of increased spatial resolution image data. The method further includes performing a pharmacokinetic (1230) analysis to obtain data including at least one parameter that characterizes the tissue, providing multiparameter look-up table derived from a combination of two or more parameters, and providing a display including one parameter or a parameteric image, where the parametric image is derived from the look-up table.