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METHOD FOR ESTIMATING THE QUANTITY OF A CHEMICALLY BONDED ORGANIC SUBSTANCE WITH A NANODIAMOND

机译:纳米金刚石估算化学键合有机物数量的方法

摘要

The invention relates to the field of pharmacy, and specifically to pharmaceutical technology, and relates to a method for estimating the quantity of chemically bonded organic substances, primarily biologically active and medicinal substances, with the surface of a nanodiamond in the conjugate thereof. The method is based on the use of a procedure for quantitative IR spectroscopy of the conjugate and model mixtures of the organic substance being determined with a nanodiamond. Calibration curves of the dependence of the "intensity of a signal in the IR spectrum on the quantity of organic substance" in the model mixture are produced and the content of said substance in the conjugate is determined on the basis of said calibration curves.
机译:本发明涉及制药领域,特别是涉及制药技术,并且涉及一种估计结合有纳米金刚石表面的化学键合的有机物质,主要是生物活性和药用物质的量的方法。该方法基于对结合物进行定量IR光谱分析的方法的使用,以及使用纳米金刚石确定有机物质的模型混合物的方法。在模型混合物中产生“ IR光谱中的信号强度与有机物质的量”相关性的校准曲线,并根据所述校准曲线确定缀合物中所述物质的含量。

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