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EARLY CHILDHOOD MEMBRANOUS NEPHROPATHY DUE TO CATIONIC BOVINE SERUM ALBUMIN
EARLY CHILDHOOD MEMBRANOUS NEPHROPATHY DUE TO CATIONIC BOVINE SERUM ALBUMIN
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机译:阳离子牛血清白蛋白引起的早期儿童膜性肾病
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摘要
The invention concerns a biomarker for diagnosing or prognosing childhood Membranous Nephropathy (MN), said biomarker is (i) cationic Bovine Serum Albumin (BSA), and/or (ii) an antibody that binds to a polypeptide of sequence SEQ ID NO: 3. The invention further concerns an antibody or antibody fragment or a composition comprising such an antibody or antibody fragment, wherein said antibody or antibody fragment is specific to an amino acid sequence SEQ ID NO: 3. The invention also concerns a foodstuff likely to contain BSA or cow milk or cow milk extracts, wherein said foodstuff is depleted in BSA.
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机译:本发明涉及用于诊断或预后儿童膜性肾病(MN)的生物标志物,所述生物标志物是(i)阳离子牛血清白蛋白(BSA),和/或(ii)与序列SEQ ID NO:3的多肽结合的抗体。本发明进一步涉及抗体或抗体片段或包含这种抗体或抗体片段的组合物,其中所述抗体或抗体片段对氨基酸序列SEQ ID NO:3具有特异性。本发明还涉及可能含有BSA的食品。或牛奶或牛奶提取物,其中所述食品中的BSA贫化。
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