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CELL CULTURE MEASURING SYSTEM AND METHOD FOR COMPARATIVE INVESTIGATIONS ON CELL CULTURES

机译:用于细胞培养的比较研究的细胞培养测量系统和方法

摘要

The invention relates to a cell culture measuring system and to a method for comparative investigations on cell cultures. It is an object of the invention to propose possibilities allowing comparative investigations on cell cultures, with identical conditions on cells influenced by test liquid and cells not influenced by test liquid. In a cell culture measuring system according to the invention, cell cultures are cultivated on a cell culture support inside a flow channel. An inflow and an outflow for a liquid culture medium and at least two sensors are present. In addition, at least one further inflow for a test liquid in the direction of flow of the culture medium between the inflow for the culture medium and the outflow of the flow channel is disposed so that, through a displacement of the culture medium, the test liquid flowing through the flow channel flows around and/or over only a part of the cells present on the cell culture support. In addition, at least one sensor is disposed in the region of the cells uninfluenced by test liquid and at least one further sensor is disposed in the region of cells influenced by test liquid.
机译:本发明涉及细胞培养物测量系统和用于细胞培养物的比较研究的方法。发明内容本发明的目的是提出一种可能性,允许对细胞培养物进行比较研究,其中在受测试液体影响的细胞和不受测试液体影响的细胞上具有相同条件。在根据本发明的细胞培养物测量系统中,细胞培养物在流道内的细胞培养物支持物上培养。存在液体培养基和至少两个传感器的流入和流出。此外,在培养基的流入和流动通道的流出之间设置至少另一种在培养基的流动方向上的供测试液体的流入,使得通过培养基的移动来进行测试流过流动通道的液体仅在细胞培养载体上存在的部分细胞周围和/或上方流动。此外,至少一个传感器布置在不受测试液体影响的细胞区域中,并且至少一个另外的传感器布置在受测试液体影响的细胞区域中。

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