Methods for detecting and analyzing n-glycolylneuraminic acid (Neu5Gc) specific antibodies in biological materials

摘要

The present invention relates to a method of detecting anti-Neu5Gc specific antibodies in a biological material comprising the steps of:(a) determining the amount of anti-Neu5Ac antibodies present in the material using Neu5Ac as an antigen target;(b) determining the amount of anti-Neu5Gc antibodies present in the material using anti-Neu5Gc as an antigen target; and(c) subtracting the amount of anti-Neu5Ac antibodies from the amount of anti-Neu5Gc antibodies to determine the amount of anti-Neu5Gc specific antibodies.