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Sustained release tablets with hydromorphone

机译:氢吗啡酮缓释片

摘要

Tablet comprises a tablet core made of several active agents containing pellet and one or more auxiliary materials, where: at least a coating is applied on the tablet core; and the pellet contains an active agent of hydromorphone or its salts and/or solvate, and exhibits the following structure: an inert core, an active agent layer applied on the inert core, a layer applied on the active agent layer, which retards the release of active agent, and a further layer applied on the layer retarding the release of active agent. An independent claim is included for the active agent containing pellets with hydromorphone.
机译:片剂包括由几种包含丸剂和一种或多种辅助材料的活性剂制成的片剂核,其中:在片剂核上至少涂覆一层包衣;所述丸粒包含氢吗啡酮或其盐和/或溶剂化物的活性剂,并具有以下结构:惰性核,涂覆在惰性核上的活性剂层,涂覆在活性剂层上的,延迟释放的层一层活性剂,并且在该层上施加的另一层阻止了活性剂的释放。对于包含具有氢吗啡酮的活性剂的丸剂,包括独立的权利要求。

著录项

  • 公开/公告号EP2425822B1

    专利类型

  • 公开/公告日2012-12-19

    原文格式PDF

  • 申请/专利权人 ACINO PHARMA AG;

    申请/专利号EP20110191245

  • 发明设计人 REHER MARKUS;ZINGRAFF MARC;

    申请日2008-10-24

  • 分类号A61K9/16;A61K9/20;A61K31/485;

  • 国家 EP

  • 入库时间 2022-08-21 16:32:54

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